Citation: Takotsubo cardiomyopathy case series: typical, atypical and
recurrence.
BMJ Case Rep. 2015;2015
Authors: Lagan J, Connor V, Saravanan P
Abstract: Takotsubo cardiomyopathy (TCM) is characterised by a transient
left ventricular (LV) dysfunction, ECG changes that can imitate acute myocardial
infarction and positive cardiac biomarkers in the absence of obstructive
coronary artery disease. The exact pathogenesis of TCM is unclear but emotional
or physical stress is a common denominator. We present three cases encompassing
a spectrum of the disease: A typical TCM with apical LV dyskinesis, an atypical
TCM with mid-ventricular regions affected and a TCM recurrence. Our cases show
that TCM symptoms vary between individuals and may vary in the same patient. All
our patients reported acute emotional stress prior to the onset of symptoms, had
LV systolic dysfunction, positive cardiac biomarkers and non-obstructed coronary
arteries. In all cases, LV systolic dysfunction eventually improved. TCM may
account for 0.7-2.5% of acute coronary syndromes. It is more prevalent in the
female population and can reoccur. Treatment is mainly supportive.
PMID: 25743867 [PubMed - in process]
Link to Pubmed record
