FREE Cancer Study Day

WHAT IS GOING ON IN CANCER NURSING AT WUTH?

Find out more at our FREE Cancer Study Day

VENUE:              ARROWE PARK HOSPITAL

LECTURE THEATRE

EDUCATION CENTRE

DATE & TIME:   THURSDAY 13^th July 1pm to 5pm

Chaired by Dawn Miller, Macmillan Lead Cancer Nurse

Topics to Include:

Skin cancer – Prevention and early detection

Stoma management following bowel cancer

Breast cancer – Health & Wellbeing Clinics

Patients Perspective

Holistic Needs Assessment - Challenges in head and neck cancer

Lung cancer – setting up a support group

Advances in management of pleural effusions

Cancer of unknown primary

Record of Care at End of Life

Integrated Specialist Palliative Care Team

FREE TEA & COFFEE

PARKING AVAILABLE

To book a place contact the Palliative Care Secretaries before 1^st July

Email:  wuth.palliativecaresecretary@nhs.net  or Phone: 0151 552 1892

Clinical decision support session

A million decisions are made in healthcare every day.  Come and find out how the Library & Knowledge Service can support you to make robust decisions in your specialty.  This drop-in session offers you the opportunity to:

·         Experience demos of our clinical decision support tools, UpToDate and Dynamed Plus

·         Register for the UpToDate and Dynamed Plus apps so that you access best evidence via your mobile device

·         Get expert advice for your evidence search, literature review or academic work

·         Pick up some library goodies including pens and post-it notes

Call in to the McArdle Library IT Suite (Education Centre, Arrowe Park) any time between 8am and 10am on Tuesday 6^th June – and invite your colleagues!

For more details (or if you’d like us to visit your department) please contact the Library & Knowledge Service on ext. 8610, wuth.lks@nhs.net.

Randomised Chocolate Trial

Testing the effects of chocolate consumption was undertaken during a Randomised Chocolate Trial in celebration of International Clinical Trials Day, Friday 19th May. The event which attracted 100 recruits explored the question “Does milk chocolate or white chocolate improve wellbeing?”
The Research Department along with the Library and Knowledge Service celebrated International Clinical Trials Day by holding a Randomised Chocolate Trial. Colleagues were invited to participate and the aim was to highlight the importance of research in healthcare as well as to help participants understand how clinical trials work.

Here are the results.​

WUTH publication: Peripheral retinopathy associated with Waldenström's macroglobulinaemia

Citation: Postgraduate Medical Journal. 2017 May 15
Author: Agorogiannis E, Sultan Z, Ramasamy B

Link to PubMed record

WUTH publication: Non-classic EGFR mutations in a cohort of Dutch EGFR-mutated NSCLC patients and outcomes following EGFR-TKI treatment

Citation: British Journal of Cancer. 2016, 115(12), 1504-1512
Author: Kuiper JL, Hashemi SM, Thunnissen E, Snijders PJ, Grünberg K, Bloemena E, Sie D, Postmus PE, Heideman DA, Smit EF
Abstract: BACKGROUND: Data on non-small-cell lung cancer (NSCLC) patients with non-classic epidermal growth factor receptor (EGFR) mutations are scarce, especially in non-Asian populations. The purpose of this study was to evaluate prevalence, clinical characteristics and outcome on EGFR-TKI treatment according to type of EGFR mutation in a Dutch cohort of NSCLC patients.
METHODS: We retrospectively evaluated a cohort of 240 EGFR-mutated NSCLC patients. Data on demographics, clinical and tumour-related features, EGFR-TKI treatment and clinical outcome were collected and compared between patients with classic EGFR mutations, EGFR exon 20 insertions and other uncommon EGFR mutations.
RESULTS: Classic EGFR mutations were detected in 186 patients (77.5%) and non-classic EGFR mutations in 54 patients (22.5%); 23 patients with an exon 20 insertion (9.6%) and 31 patients with an uncommon EGFR mutation (12.9%). Median progression-free survival (PFS) and overall survival (OS) on EGFR-TKI treatment were 2.9 and 9.7 months, respectively, for patients with an EGFR exon 20 insertion, and 6.4 and 20.2 months, respectively, for patients with an uncommon EGFR mutation. Patients with a double uncommon EGFR mutation that included G719X/L861Q/S768I had longer PFS and OS on EGFR-TKI treatment compared with patients with a single G719X/L861Q/S768I EGFR mutation (both P=0.02).
CONCLUSIONS: In our Dutch cohort, prevalence and genotype distribution of non-classic EGFR mutations were in accordance with previously reported data. The PFS and OS on EGFR-TKI treatment in patients with an uncommon EGFR mutation were shorter compared with patients with classic EGFR mutations, but varied among different uncommon EGFR mutations.

Link to PubMed record

WUTH publication: Optimizing a career in surgery

Citation: British Journal of Hospital Medicine. 2017, 78(5), C70-C73
Author: Mehta N, Platt S

Link to PubMed record

Randomised Chocolate Trial

If you like the idea of testing the effects of chocolate consumption, come along and take part in a Randomised Chocolate Trial in celebration of International Clinical Trials Day 2017.
The Research Department along with the Library and Knowledge Service will be celebrating International Clinical Trials Day by holding a Randomised Chocolate Trial. Colleagues are invited to participate and the aim is to highlight the importance of research in healthcare as well as to help participants understand how clinical trials work.
The event will be a ‘drop-in-session’ anytime from noon until 2 pm in Rooms A & B, Clinical Skills, D-Block, Arrowe Park Hospital on Friday 19th May.
No need to book, just turn up and bring your colleagues with you. The results of our trial will be published after the study.

WUTH publication: Ancient schwannoma in the sublingual space masquerading as a plunging ranula

Citation: Journal of Surgical Case Reports. 2017 Apr 4
Author: Vallabh N, Srinivasan V, Hughes D, Agbamu D
Abstract: Ancient schwannomas are benign, slow-growing tumours derived from the neural sheath. They are characterized by degenerative changes which are not seen in the common schwannoma. An unusual case of ancient schwannoma of the sublingual space is reported to highlight the diagnostic challenge that this tumour presents. A 49-year-old male patient presented with an 8-month history of a right-sided neck swelling, palpable in the anterior part of the submandibular triangle. Pre-operative imaging showed a non-enhancing mass in the sublingual space spilling into the submandibular triangle, consistent with a plunging ranula. Fine needle aspiration cytology was inconclusive. However, histopathology of the lesion confirmed the diagnosis of an ancient schwannoma, which is seldom found in the sublingual space.

Link to PubMed record