Citation: Ecancermedicalscience. 2016 Dec 1
Author: Ormsby NM, Leong WY, Wong W, Hughes HE, Swaminathan V
Abstract: The most common site for cancer to spread is bone. At post-mortem, bony metastases have been found in 70% of patients dying from breast and prostate cancer. Due to the prevalence of cancer, bone metastasis and the associated management represents a huge burden on NHS resources. In patients with metastasis, around 56% of these involve the lower limb long bones. Due to the huge forces placed upon long bones during weight bearing, there is a high risk of fracture through areas of metastasis. It is reported that 23% of pathological fractures occur in the femoral subtrochanteric region. This area is subjected to forces up to four times the body weight, resulting in poor union rate for these fractures, and significant morbidity associated with difficulty in mobilising, and in patient nursing. As cancer treatments improve, the life expectancy in this subgroup of patients is likely to increase. Therefore medium-to-long-term management of these fractures, beyond the palliative, will become essential. We aim to evaluate the current management for metastatic malignant femoral disease, with particular focus on the prophylactic augmentation of diseased femorii using intramedullary nails.
KEYWORDS:
arthroplasty; internal fixation; intramedullary nailing; metastatic cancer; pathological fracture; prophylactic nailing
Link to PubMed record
Monday 23 January 2017
Friday 13 January 2017
Allied Health Professions (AHP) Research Bursary
The Cheshire & Merseyside AHP Research Network is offering bursaries of up to £1000 to facilitate small scale research studies conducted and led by AHPs.
Please note these applications are only open to AHPs (registered with HCPC) who work in the Cheshire & Merseyside region.
The applicant is expected to complete a small research project and provide a written report of results.
Examples of suitable studies may include pilot work (small scale preliminary studies) and proof of concept (feasibility studies collecting and analysing data to obtain evidence to support or refute ideas or plans). Preference will be given to projects that incorporate patient and public involvement.
Funding may be used in a number of ways, for example:
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For training – for help with statistics, surveys, interviews, etc,
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Only direct costs can be covered by the Bursary.
The applicant is expected to forge a link with their NHS Trust Research office and establish a mentor within the Trust, who will be able to provide support.
Applicants should submit their application form via email by Monday 27th February 2017, 5pm to rowef@liverpool.ac.uk.
Please note these applications are only open to AHPs (registered with HCPC) who work in the Cheshire & Merseyside region.
The applicant is expected to complete a small research project and provide a written report of results.
Examples of suitable studies may include pilot work (small scale preliminary studies) and proof of concept (feasibility studies collecting and analysing data to obtain evidence to support or refute ideas or plans). Preference will be given to projects that incorporate patient and public involvement.
Funding may be used in a number of ways, for example:
To back fill staff time – release researcher from clinical duties to undertake the research,
For training – for help with statistics, surveys, interviews, etc,
For transcription costs,
For payment of patient and public expenses.
Only direct costs can be covered by the Bursary.
The applicant is expected to forge a link with their NHS Trust Research office and establish a mentor within the Trust, who will be able to provide support.
Applicants should submit their application form via email by Monday 27th February 2017, 5pm to rowef@liverpool.ac.uk.
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