Citation: The British journal of ophthalmology. 2014, 98(8), 1080-6
Author: Park JC, Ramasamy B, Shaw S, Ling RH, Prasad S
Abstract: BACKGROUND/AIMS: This is the first prospective and nationwide study aiming to
provide epidemiological data relating to presentation, microbiology, management
and outcome of endophthalmitis following vitrectomy.
METHODS: Two years of
prospective and nationwide surveillance for cases of presumed infectious
endophthalmitis within 6 weeks of pars plana vitrectomy was completed. The study
obtained case reports via the established British Ophthalmological Surveillance
Unit (BOSU) system.
RESULTS: Thirty-seven cases were reported and 28 met the
diagnostic criteria for presumed infectious endophthalmitis following
vitrectomy. Mean age was 61 years and 67% were male. Nineteen cases were 23/25
gauge and 9 cases were 20 gauge. Mean time from surgery to endophthalmitis was
5 days. Blurred vision (85.2%), pain (77.8%) and a hypopyon (77.8%) were the
commonest presenting symptoms and signs. Seventeen cases (60.7%) had a positive
culture. Culture-positive endophthalmitis, relative to culture-negative
endophthalmitis, was no different with respect to time to presentation,
symptoms, signs or outcome. Outcome was poor, with 29.6% of eyes being
eviscerated or having no perception of light or perception of
light.
CONCLUSIONS: This study helps surgeons promptly identify cases of
endophthalmitis following vitrectomy and informs them about the various
management options currently used and the likely outcome of this devastating
complication.
Link to PubMed record.
