Author: Azhar U.A.; Seneviratne R.H.
Abstract: Epidermoid cyst is a rare and non-teratomatous benign tumour of the testis. It cannot be differentiated reliably from the far more common malignant testicular mass on a clinical basis. Testicular epidermoid cysts are of two types, occurring through one of two possible lineages proposed; those of monodermal teratoma origin and those of invaginated mesothelial origin. Intratubular germ cell neoplasia is not reported in association with true testicular epidermoid cysts, which are defined, mainly by the absence of scarring and absence of any dermal appendages and sebaceous glands. We here by report three cases of
epidermoid cyst of testis in young boys aged 11, 14 and 18. In all three cases the clinical information on the form mentioned testicular mass with negative tumour markers. The histological examination showed a fibrous cyst capsule lined by well-differentiated squamous epithelium that surrounded a cavity of laminated keratin. Negative immunohistochemistry ruled out intratubular germ cell neoplasia in these cases. The absence of mesodermal and endodermal components distinguished this from dermoid cyst or teratomas. Radical orchiectomy has been extensively carried out earlier but some authors have lately encouraged testis-sparing surgery in adults.
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